產(chǎn)地：荷蘭 動(dòng)物步態(tài)分析系統(tǒng)Catwalk XT是什么 為什么要使用動(dòng)物步態(tài)分析系統(tǒng)
是一個(gè)定量分析嚙齒類動(dòng)物模型腳步和步態(tài)的完整系統(tǒng)。
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封閉的走道可以方便的評(píng)估非受迫動(dòng)物移動(dòng)的腳印及步態(tài)，獲得自然步態(tài)。
Illuminated Footprints™技術(shù)捕獲真實(shí)動(dòng)態(tài)的腳印。
Illuminated Footprints™技術(shù)可以實(shí)現(xiàn)身體重量分配測(cè)量。 
動(dòng)物步態(tài)分析系統(tǒng)是如何工作的
CatWalk XT動(dòng)物步態(tài)分析系統(tǒng)是一個(gè)包含軟硬件的完整系統(tǒng)。它使用Illuminated Footprints™技術(shù)，捕獲每一個(gè)腳步的細(xì)節(jié)。通過自動(dòng)腳印分類節(jié)省您大量的實(shí)驗(yàn)時(shí)間。
動(dòng)物步態(tài)分析系統(tǒng)的核心設(shè)備是一個(gè)封閉的步行臺(tái)，老鼠可以從一端走到另一端。腳印照明技術(shù)實(shí)現(xiàn)了利用高速攝像機(jī)從步行臺(tái)下方捕獲真正的腳印。
腳印照明技術(shù)甚至可以探測(cè)壓力差異，從而測(cè)量動(dòng)物體重在四腳的分配情況。
為了動(dòng)物保持自然步態(tài)沒有采取強(qiáng)制措施。在步態(tài)分析中行走速度是一個(gè)非常重要的因素。步態(tài)分析系統(tǒng)可以測(cè)定行走速度，進(jìn)行數(shù)據(jù)選擇和分析。不需要外部標(biāo)記，修剪指甲，大量光照等。
測(cè)量的參數(shù)包括，著地時(shí)間，懸空時(shí)間，步長，壓力，左右腳間距，前后腳印記間距，步序等。
誰適合使用動(dòng)物步態(tài)分析系統(tǒng)
以下研究領(lǐng)域可以使用動(dòng)物步態(tài)分析系統(tǒng)CatWalk XT進(jìn)行損傷，恢復(fù)，藥物干預(yù)等方面的評(píng)估。
神經(jīng)損傷 神經(jīng)退行性變 神經(jīng)疾病 疼痛癥狀 脊髓損傷 神經(jīng)性疼痛 關(guān)節(jié)炎 中風(fēng) 帕金森癥 運(yùn)動(dòng)失調(diào) 創(chuàng)傷性腦損傷（TBI） 末梢神經(jīng)損傷
交互式腳印測(cè)量功能
新的交互式腳印測(cè)量擴(kuò)展模塊可以測(cè)量下列參數(shù)：
• 遠(yuǎn)趾端開口距
• 近趾端開口距
• 腳印長度
• 腳爪朝向
趾端開口距和腳印長度用來計(jì)算坐骨神經(jīng)功能指數(shù)。該指數(shù)用于評(píng)估鼠類的坐骨神經(jīng)功能恢復(fù)情況。 
數(shù)據(jù)分段概要功能
動(dòng)物步態(tài)分析系統(tǒng)9.0提供了數(shù)據(jù)分段概要功能，允許您根據(jù)速度參數(shù)和連續(xù)步行的次數(shù)選擇動(dòng)物步行片段，從而提高您的試驗(yàn)數(shù)據(jù)質(zhì)量并允許您控制動(dòng)物運(yùn)動(dòng)速度。
新增統(tǒng)計(jì)參數(shù)
在動(dòng)物步態(tài)分析系統(tǒng)9.0中除了新增的腳印測(cè)量參數(shù)，用來計(jì)算坐骨神經(jīng)功能指數(shù)。另外，新的參數(shù)還有：單足支撐時(shí)間，起始雙足支撐時(shí)間，末尾雙足支撐時(shí)間。這些參數(shù)用于研究疼痛實(shí)驗(yàn)中動(dòng)物的單只和雙只后腿支撐所用時(shí)間。
足印自動(dòng)分類功能
動(dòng)物步態(tài)分析系統(tǒng)包括了足印自動(dòng)分類功能。只需按動(dòng)按鈕，系統(tǒng)將自動(dòng)分類動(dòng)物步行過程中的足印。如果系統(tǒng)提示不能分類的足印，系統(tǒng)會(huì)自動(dòng)突出這些足印方便您手動(dòng)標(biāo)記。前期測(cè)試結(jié)果令人印象深刻：在足印分類中節(jié)省了高達(dá)70%的時(shí)間，從而使整個(gè)實(shí)驗(yàn)的時(shí)間也節(jié)約了50%。的物有所值！
“在各種不同的動(dòng)物模型中，足印自動(dòng)分類技術(shù)都表現(xiàn)的很出色。腳爪探測(cè)非?？煽?，大多數(shù)的探測(cè)失誤的爪印都是由于步行臺(tái)上的污跡?？梢愿鶕?jù)足印和時(shí)間視圖能夠很容易識(shí)別有錯(cuò)誤的片段，從而使您手動(dòng)修改。超過90%的腳印分類都不需要改正。對(duì)于實(shí)驗(yàn)人員來說足印分類也成了一項(xiàng)有趣的工作” 法國賽諾菲安萬特制藥集團(tuán)(Sanofi-Aventis)的Frankfurt博士這樣評(píng)價(jià)道。
技術(shù)參數(shù)：
參考文獻(xiàn)
The CatWalk gait analysis in assessment of both dynamic and static gait changes after adult rat sciatic nerve resection
R Deumens, RJP Jaken, MAE Marcus, EAJ … - Journal of neuroscience …, 2007 - Elsevier
Functional repair of neurotmesis has been proven most challenging in regenerative
medicine. Progress in this field has shown that functional repair not only requires axon
regeneration, but also selectivity in target reinnervation. Although selectivity in target ...
CatWalk gait analysis in assessment of functional recovery after sciatic nerve injury
A Bozkurt, R Deumens, J Scheffel, DM O'Dey, J … - Journal of neuroscience …, 2008 - Elsevier
Following peripheral nerve injury repair, improved behavioural outcome may be the most important
evidence of functionality oon regeneration after any repair strategy. A range of behavioural
testing paradigms have been developed for peripheral nerve injury research. Complete ...
Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries
FPT Hamers, AJ Lankhorst, TJ van Laar, WB … - Journal of …, 2001 -
... During a first automatic pass the bright areas in the individual frames are labeled and
in- dexed; in the subsequent pass, these spots are interactively CATWALK GAIT
ANALYSIS 189 Page 4. ... Page 5. CATWALK GAIT ANALYSIS 191 FIG. ...
CatWalk'automated quantitative gait analysis as a novel method to assess mechanical allodynia in the rat; a comparison with von Frey testing
DH Vrinten, FFT Hamers - Pain, 2003 - Elsevier
A characteristic symptom of neuropathic pain is mechanical allodynia. In animal models of neuropathic
pain, mechanical allodynia is often assessed using von Frey filaments. Although the forces applied
with these filaments are highly reproducible, there are various disadvantages of using this ...
CatWalk-assisted gait analysis in the assessment of spinal cord injury
FPT Hamers, GC Koopmans, EAJ … - Journal of …, 2006 -
Gait analysis plays an important role in the assessment of neurological function in many disease
models. In this review, we focus on the newly developed CatWalk system for gait analysis. CatWalk
was originally developed as a tool to enhance assessment of functional outcome in spinal ...
The CatWalk method: Assessment of mechanical allodynia in experimental chronic pain
AF Gabriel, MAE Marcus, GHIM Walenkamp, … - Behavioural brain …, 2009 - Elsevier
... Available online 25 December 2008. Abstract. The CatWalk gait analysis system has recently
been suggested as a rapid and objective alternative method over the von Frey test to assess
mechanical allodynia in chronic neuropathic pain models. ...
注：本產(chǎn)品是主要用于科學(xué)研究的實(shí)驗(yàn)儀器。非臨床醫(yī)療設(shè)備。
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